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Báo cáo y học: "Perioperative factors determine outcome after surgery for severe acute pancreatitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Perioperative factors determine outcome after surgery for severe acute pancreatitis. | Available online http ccforum.eom content 8 6 R504 Research Perioperative factors determine outcome after surgery for severe acute pancreatitis Jan J De Waele1 Eric Hoste1 Stijn I Blot2 Uwe Hesse3 Piet Pattyn3 Bernard de Hemptinne3 Johan Decruyenaere1 Dirk Vogelaers4 and Francis Colardyn1 Open Access Intensivist Intensive Care Unit Ghent University Hospital Gent Belgium 2Researcher Intensive Care Unit Ghent University Hospital Gent Belgium 3Surgeon Intensive Care Unit Ghent University Hospital Gent Belgium 4Infectious Diseases Consultant Department of Surgery Ghent University Hospital Gent Belgium Corresponding author Jan J De Waele jan.dewaele@UGent.be Received 15 July 2004 Revisions requested 3 September 2004 Revisions received 22 September 2004 Accepted 7 October 2004 Published 2 November 2004 Critical Care 2004 8 R504-R511 DOI 10.1186 cc2991 This article is online at http ccforum.com content 8 6 R504 2004 De Waele et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction There is evidence that postponing surgery in critically ill patients with severe acute pancreatitis SAP leads to improved survival but previous reports included patients with both sterile and infected pancreatic necrosis who were operated on for various indications and with different degrees of organ dysfunction at the moment of surgery which might be an important bias. The objective of this study is to analyze the impact of timing of surgery and perioperative factors severity of organ dysfunction and microbiological status of the necrosis on mortality in intensive care unit ICU patients undergoing surgery for SAP. Methods We retrospectively January 1994 to March 2003 analyzed patients admitted to the ICU with SAP. Of 124 patients 56