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Báo cáo khoa học: "Minimally invasive cardiopulmonary bypass: does it really change the outcome"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Minimally invasive cardiopulmonary bypass: does it really change the outcome? | Available online http ccforum.eom content 11 2 R45 Research Minimally invasive cardiopulmonary bypass does it really change the outcome Marco Ranucci and Giuseppe Isgrò Department of Cardiovascular Anesthesia and Intensive Care IRCCS Policlinico S. Donato Via Morandi 30 San Donato Milanese Milan - 20097 Italy Corresponding author Marco Ranucci cardioanestesia@virgilio.it Received 11 Jan 2007 Revisions requested 20 Feb 2007 Revisions received 4 Mar 2007 Accepted 15 Apr 2007 Published 15 Apr 2007 Critical Care 2007 11 R45 doi 10.1186 cc5777 This article is online at http ccforum.com content 11 2 R45 2007 Ranucci and Isgrò licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Many innovative cardiopulmonary bypass CPB systems have recently been proposed by the industry. With few differences they all share a philosophy based on priming volume reduction closed circuit with separation of the surgical field suction centrifugal pump and biocompatible circuit and oxygenator. These minimally invasive CPB MICPB systems are intended to limit the deleterious effects of a conventional CPB. However no evidence exists with respect to their effectiveness in improving the postoperative outcome in a large population of patients. This study aimed to verify the clinical impact of an MICPB in a large population of patients undergoing coronary artery revascularization. Methods We conducted a retrospective analysis of 1 663 patients treated with an MICPB. The control group conventional CPB was extracted from a series of 2 877 patients according to a propensity score analysis. Results Patients receiving an MICPB had a shorter intensive care unit ICU stay had lower peak postoperative serum creatinine and bilirubin levels