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Báo cáo y học: " Involvement of claudin-7 in HIV infection of CD4(-) cells"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Involvement of claudin-7 in HIV infection of CD4(-) cells | Retrovirology BioMed Central Research Involvement of claudin-7 in HIV infection of CD4 - cells Junying Zheng1 Yiming Xie2 Richard Campbell4 Jun Song1 Samira Massachi1 Miriam Razi1 Robert Chiu1 James Berenson4 Otto O Yang3 Irvin SY Chen2 and Shen Pang 1 Open Access Address 1UCLA School of Dentistry UCLA Dental Institute and Jonsson Comprehensive Cancer Center 10833 Le Conte Ave. Los Angeles CA 90095 USA 2Departments of Medicine and Microbiology Immunology and UCLA AIDS Institute David Geffen School of Medicine at UCLA 10833 Le Conte Ave. Los Angeles CA 90095 USA 3Department of Medicine Div. of Infectious Diseases David Geffen School of Medicine at UCLA 10833 Le Conte Ave. Los Angeles CA 90095 USA and 4Institute for Myeloma Bone Cancer Research 9201 Sunset Blvd. Suite 300 West Hollywood CA90069 USA Email Junying Zheng - zyzheng29@hotmail.com Yiming Xie - yxie@ucla.edu Richard Campbell - rcampbell@myelomasource.org Jun Song - junsong@ucla.edu Samira Massachi - shekar55@aol.com Miriam Razi - MRazi1@aol.com Robert Chiu - rchiu@dent.ucla.edu James Berenson - cjames@myelomasource.org Otto O Yang - OYang@mednet.ucla.edu Irvin SY Chen - ichen@ucla.edu Shen Pang - shenp@dent.ucla.edu Corresponding author Published 20 December 2005 Received 07 September 2005 Accepted 20 December 2005 Retrovirology 2005 2 79 doi l0.ll86 l 742-4690-2-79 H This article is available from http www.retrovirology.cOm content 2 1 79 2005 Zheng et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Human immunodeficiency virus HIV infection of CD4 - cells has been demonstrated and this may be an important mechanism for HIV transmission. Results We demonstrated that a membrane protein claudin-7 CLDN-7 is involved in HIV infection of CD4 - .

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