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Báo cáo y học: " Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease | Retrovirology BioMed Central Research Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease Open Access Maria Yakova41 2 Agnès Lézint1 3 Fabienne Dantin3 Gisèle Lagathu3 Stéphane Olindo4 Georges Jean-Baptiste2 Serge Arfi2 and Raymond Césaire 1 3 Address 1INSERM UMR433 antenne du Centre hospitalier universitaire de Fort-de-France Martinique 2Service de Médecine interne et Rhumatologie Centre hospitalier universitaire de Fort-de-France Martinique 3Laboratoire de Virologie-Immunologie Centre hospitalier universitaire de Fort-de-France Martinique and 4Service de Neurologie Centre hospitalier universitaire de Fort-de-France Martinique Email Maria Yakova - mariayakova@hotmail.com Agnès Lézin - a_lezin@yahoo.fr Fabienne Dantin - fabienne.dantin@chu-fortdefrance.fr Gisèle Lagathu - gisele.lagathu@chu-fortdefrance.fr Stéphane Olindo - olindo.stephane@wanadoo.fr Georges Jean- Baptiste - gcd.jeanbaptiste@wanadoo.fr Serge Arfi - serge.arfi@chu-fortdefrance.fr Raymond Césaire - raymond.cesaire@chu-fortdefrance.fr Corresponding author fEqual contributors Published 01 February 2005 Received 26 October 2004 Accepted 01 February 2005 Retrovirology 2005 2 4 doi l0.ll 86 1742-4690-2-4 This article is available from http www.retrovirology.cOm content 2 1 4 2005 Yakova et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Human T-lymphotropic virus type 1 HTLV-1 proviral load is related to the development of HTLV-1-associated myelopathy tropical spastic paraparesis HAM TSP and has also been shown to be elevated in the peripheral blood in HTLV-1-infected patients with uveitis or alveolitis. Increased proliferation of HTLV-1-infected cells in or migration of such cells into