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Báo cáo y học: "Recent literature regarding tight glycemic control: pitfalls in the sweet debate"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Recent literature regarding tight glycemic control: pitfalls in the sweet debate. | Available online http ccforum.eom content 13 2 408 Letter Recent literature regarding tight glycemic control pitfalls in the sweet debate Robert C Osburne1 Paul C Davidson1 Lawrence Stockton2 Marianne Baird3 Lisa Kiblinger3 and R Dennis Steed4 for the Diabetes Special Interest Group of the Partnership for Health and Accountability Atlanta Diabetes Associates 77 Collier Road 2080 Atlanta GA 30309 USA 2Piedmont Mountainside Hospital 1266 Highway 515 South Jasper GA 30143 USA 3Saint Josephs Hospital 5665 Peachtree Dunwoody Road N.E. Atlanta GA 30342 USA 4South Eastern Endocrinology and Diabetes 1475 Holcomb Bridge Road Suite 129 Roswell GA 30076 USA Corresponding author Robert C Osburne robert.osburne@mindspring.com Published 30 April 2009 This article is online at http ccforum.com content 13 2 408 2009 BioMed Central Ltd Critical Care 2009 13 408 doi 10.1186 cc7750 Articles concluding that tight glycemic control TGC in the intensive care unit ICU has no mortality benefit and an unacceptably high rate of hypoglycemia have been published recently in several journals. The Diabetes Special Interest Group DSIG 1 believes that the data from some of these recent papers have been interpreted incorrectly misconstrued or misunderstood. The DSIG agrees with the scientists whose editorial comments were published with these articles 2 3 that the studies were underpowered to show a lack of benefit and agrees that hypoglycemia below 40 mg dL is an undesirable complication. The incidence of hypoglycemia in these studies compares unfavorably with data from results with the Glucommander which in published data has an overall hypoglycemia rate below 40 mg dL of only 2.6 4 and more recently no blood sugar below 40 mg dL was seen in patients on the Glucommander in the cardiovascular ICU 5 . Algorithms for achieving TGC are being continually refined. The target ranges for ICU patients are firmly established in only the post-cardiac surgical population. The DSIG joins others in the hope .