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Báo cáo y học: "Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains. | Research Open Access Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains Elizabeth E Slawson Christopher D Shaffer Colin D Malone Wilson Leung Elmer Kellmann Rachel B Shevchek Carolyn A Craig Seth M Bloom James Bogenpohl II James Dee Emiko TA Morimoto Jenny Myoung Andrew S Nett Fatih Ozsolak Mindy E Tittiger Andrea Zeug Mary-Lou Pardue Jeremy Buhler Elaine R Mardis and Sarah CR Elgin Addresses Biology Department Washington University St Louis MO 63130 USA. Member Bio 4342 class Washington University St Louis MO 63130 USA. Department of Biology Massachusetts Institute of Technology Cambridge MA 02139 USA. Computer Science and Engineering Washington University St Louis MO 63130 USA. Genome Sequencing Center and Department of Genetics Washington University St Louis MO 63108 USA. Correspondence Sarah CR Elgin. Email selgin@biology.wustl.edu Published 20 February 2006 Genome Biology 2006 7 R15 doi 10.1 186 gb-2006-7-2-r15 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2006 7 2 R15 Received 1 August 2005 Revised 15 September 2005 Accepted 25 January 2006 2006 Slawson et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Chromosome four of Drosophila melanogaster known as the dot chromosome is largely heterochromatic as shown by immunofluorescent staining with antibodies to heterochromatin protein 1 HP 1 and histone H3K9me. In contrast the absence of HP1 and H3K9me from the dot chromosome in D. virilis suggests that this region is euchromatic. D. virilis diverged from D. melanogaster 40 to 60 million years ago. Results Here we describe finished .

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