Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: "Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions. | Open Access Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions Stewart MacArthurH Xiao-Yong LiH Jingyi LiH James B Brown Hou Cheng Chu Lucy Zeng Brandi P Grondona Aaron Hechmer Lisa Simirenko Soile VE Keranen David W Knowles Mark Stapleton Peter Bickel Mark D Biggin and Michael B Eisen Addresses Genomics Division Lawrence Berkeley National Laboratory Cyclotron Road MS 84-181 Berkeley CA 94720 USA. Howard Hughes Medical Institute University of California Berkeley Berkeley CA 94720 USA. Department of Statistics University of California Berkeley Berkeley CA 94720 USA. Life Sciences Division Lawrence Berkeley National Laboratory Cyclotron Road MS 84-181 Berkeley CA 94720 USA. Department of Molecular and Cell Biology University of California Berkeley Berkeley CA 94720 USA. Current address Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Robinson Way Cambridge CB2 0RE UK. H These authors contributed equally to this work. Correspondence Mark D Biggin. Email MDBiggin@lbl.gov. Michael B Eisen. Email MBEisen@lbl.gov Published 23 July 2009 Genome Biology 2009 10 R80 doi 10.1186 gb-2009- 10-7-r80 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 10 7 R80 Received 26 January 2009 Revised 15 May 2009 Accepted 23 July 2009 2009 MacArthur et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background We previously established that six sequence-specific transcription factors that initiate anterior posterior patterning in Drosophila bind to overlapping sets of thousands of genomic regions in blastoderm embryos. While regions bound at .