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Báo cáo y học: "Absence of seroreversion in 80 HAART-treated HIV-1 seropositive patients with at least five-years undetectable plasma HIV-1 viral load."

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Absence of seroreversion in 80 HAART-treated HIV-1 seropositive patients with at least five-years undetectable plasma HIV-1 viral load. | AIDS Research and Therapy BioMed Central Short report Open Access Absence of seroreversion in 80 HAART-treated HIV-1 seropositive patients with at least five-years undetectable plasma HIV-1 viral load Marion Cornelissen1 Suzanne Jurriaans1 Jan M Prins2 Margreet Bakker1 and Antoinette C van der Kuyl 1 Address Department of Human Retrovirology Academic Medical Centre University of Amsterdam Amsterdam The Netherlands and 2Department of Internal Medicine Division of Infectious Diseases Tropical Medicine and AIDS Academic Medical Centre University of Amsterdam Amsterdam The Netherlands Email Marion Cornelissen - m.i.cornelissen@amc.uva.nl Suzanne Jurriaans - s.jurriaans@amc.uva.nl Jan M Prins - j.m.prins@amc.uva.nl Margreet Bakker - m.e.bakker@amc.uva.nl Antoinette C van der Kuyl - a.c.vanderkuyl@amc.uva.nl Corresponding author Published 16 February 2006 Received 19 December 2005 AIDS Research and Therapy 2006 3 3 doi 10.1186 1742-6405-3-3 Accepted 16 February 2006 This article is available from http www.aidsrestherapy.cOm content 3 1 3 2006 Cornelissen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Partial or complete seroreversion for HIV-1 or incomplete antibody evolution are relatively rare events that have so far only been described in patients treated with HAART early after virus infection. Whether seroreversion is seen in patients treated effectively with HAART years after their acute infection has not been investigated so far. Therefore we have investigated anti-HIV antibody levels in 80 patients treated with HAART during chronic HIV-1 infection who had an undetectable HIV-1 plasma viral load for at least five years. In none of the patients we observed seroreversion and there was also no significant .

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