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Báo cáo y học: "Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer. | Grutsch et al. Journal of Circadian Rhythms 2011 9 4 http www.jcircadianrhythms.eom content 9 1 4 JOURNAL OF CIRCADIAN RHYTHMS RESEARCH Open Access Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer James F Grutsch1 6 Patricia A Wood2 3 Jovelyn Du-Quiton2 3 Justin L Reynolds2 Christopher G Lis 1 Robert D Levin1 Mary Ann Daehler1 Digant Gupta1 Dinah Faith T Quiton2 4 and William JM Hrushesky1 3 4 5 Abstract Background Many cancer patients report poor sleep quality despite having adequate time and opportunity for sleep. Satisfying sleep is dependent on a healthy circadian time structure and the circadian patterns among cancer patients are quite abnormal. Wrist actigraphy has been validated with concurrent polysomnography as a reliable tool to objectively measure many standard sleep parameters as well as daily activity. Actigraphic and subjective sleep data are in agreement when determining activity-sleep patterns and sleep quality quantity each of which are severely affected in cancer patients. We investigated the relationship between actigraphic measurement of circadian organization and self-reported subjective sleep quality among patients with advanced lung cancer. Methods This cross-sectional and case control study was conducted in 84 patients with advanced non-small cell lung cancer in a hospital setting for the patients at Midwestern Regional Medical Center MRMC Zion IL USA and home setting for the patients at WJB Dorn Veterans Affairs Medical Center VAMC Columbia SC USA. Prior to chemotherapy treatment each patient s sleep-activity cycle was measured by actigraphy over a 4-7 day period and sleep quality was assessed using the Pittsburgh Sleep Quality Index PSQI questionnaire. Results The mean age of our patients was 62 years. 65 patients were males while 19 were females. 31 patients had failed prior treatment while 52 were newly diagnosed. Actigraphy and PSQI scores showed significantly disturbed .