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Báo cáo y học: "Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases. | Barbetakis et al. Journal of Cardiothoracic Surgery 2010 5 27 http www.cardiothoracicsurgery.Org content 5 1 27 Jdfrs JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Early land late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions a review of 400 cases Nikolaos Barbetakis 1 Christos Asteriou1 Fani Papadopoulou1 Georgios Samanidis1 Dimitrios Paliouras1 Athanassios Kleontas1 Konstantina Lyriti2 Ioannis Katsikas2 and ChristodoulosTsilikas1 Abstract Background Malignant pleural effusion is a common sequelae in patients with certain malignancies. It represents a terminal condition with short median survival in terms of months and the goal is palliation. Aim of our study is to analyze morbidity mortality and life expectancy following videothoracoscopic talc poudrage. Materials and methods From September 2004 to October 2009 400 patients underwent video-assisted thoracic surgery VATS for malignant pleural effusion. The conditions of patients were assessed and graded before and after treatment concerning morbidity mortality success rate of pleurodesis and median survival. Results The median duration of follow up was 40 months range 4-61 months . All patients demonstrated notable improvement in dyspnea. Intraoperative mortality was zero. The procedure was well tolerated and no significant adverse effects were observed. In hospital mortality was 2 and the pleurodesis success rate was 85 . A poor Karnofsky Performance Status and delay between diagnosis of pleural effusion and pleurodesis were statistically significant factors for in-hospital mortality. The best survival was seen in breast cancer followed by ovarian cancer lymphoma and pleural mesothelioma. Conclusions Video-assisted thoracoscopic talc poudrage is an effective and safe procedure that yields a high rate of successful pleurodesis and achieves long-term control with marked dyspnea decrease. Introduction Pleural .