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Báo cáo y học: "Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model. | Journal of Brachial Plexus and Peripheral Nerve Injury BioMed Central Research article Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model Ali Murat Kalender 1 Ali Dogan2 Vedat Bakan3 Huseyin Yildiz4 Mehmet Ata Gokalp2 and Mahmut Kalender5 Address Department of Orthopedics and Traumatology Kahramanmaras Sutcu Imam University Medical Faculty K. Maras Turkey 2Department of Orthopedics and Traumatology Yuzuncu Yil University Medical Faculty Van Turkey 3Department of Pediatric Surgery Kahramanmaras Sutcu Imam University Medical Faculty Kahramanmaras Turkey 4Department of Anesthesiology and Reanimation Kahramanmaras Sutcu Imam University Medical Faculty Kahramanmaras Turkey and 5Gaziantep Medical Center Gaziantep Turkey Email Ali Murat Kalender - kalenderalimurat@hotmail.com Ali Dogan - alidogan67@hotmail.com Vedat Bakan - vedatbakan@hotmail.com Huseyin Yildiz - dr.huseyinyildiz@mynet.com Mehmet Ata Gokalp - doktorata@hotmail.com Mahmut Kalender - ortopedia34@hotmail.com Corresponding author Open Access Published 9 June 2009 Received 22 April 2009 Journal of Brachial Plexus and Peripheral Nerve Injury 2009 4 6 doi l0.ll 86 1749-7221 -4-6 Accepted 9 June 2009 This article is available from http www.jbppni.cOm content 4 1 6 2009 Kalender et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Zofenopril is an antioxidant agent which has been shown to have beneficial effects in hypertension and heart failure. The aim of this study was to test the effects of Zofenopril on nerve regeneration and scarring in a rat model of peripheral nerve crush injury. Methods Twenty-one adult Sprague-Dawley rats underwent a