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Báo cáo y học: "The challenge to detect heart transplant rejection and transplant vasculopathy non-invasively a pilot study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The challenge to detect heart transplant rejection and transplant vasculopathy non-invasively a pilot study. | Journal of Cardiothoracic Surgery BioMed Central Open Access Research article The challenge to detect heart transplant rejection and transplant vasculopathy non-invasively a pilot study Engin Usta 1 Christof Burgstahler2 Hermann Aebert1 Stephen Schroeder2 Uwe Helber2 Andreas F Kopp3 and Gerhard Ziemer1 Address Department of Thoracic- Cardiac- and Vascular Surgery Tubingen University Hospital Germany 2Department of Internal Medicine Division of Cardiology Tubingen University Hospital Germany and 3Department of Diagnostic Radiology Tubingen University Hospital Germany Email Engin Usta - engin.usta@med.uni-tuebingen.de ChristofBurgstahler-christof.burgstahler@med.uni-tuebingen.de HermannAebert-hermann.aebert@med.uni-tuebingen.de Stephen Schroeder-stephen.schroeder@med.uni-tuebingen.de Uwe Helber - uwe.helber@med.uni-tuebingen.de Andreas F Kopp - andreas.kopp@med.uni-tuebingen.de Gerhard Ziemer - gerhard.ziemer@med.uni-tuebingen.de Corresponding author Published 16 August 2009 Received 29 March 2009 Journal of Cardiothoracic Surgery 2009 4 43 doi l0.ll86 l749-8090-4-43 Accepted 16 August 2009 This article is available from http www.cardiothoracicsurgery.Org content 4 1 43 2009 Usta et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Cardiac allograft rejection and vasculopathy are the main factors limiting long-term survival after heart transplantation. In this pilot study we investigated whether non-invasive methods are beneficial to detect cardiac allograft rejection Grade 03 R and cardiac allograft vasculopathy. Thus we compared multi-slice computed tomography and magnetic resonance imaging with invasive methods like coronary angiography and left endomyocardial biopsy. Methods 10 asymptomatic long-term