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Báo cáo y học: " Renal cell carcinoma metastasizing to solitary fibrous tumor of the pleura: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Renal cell carcinoma metastasizing to solitary fibrous tumor of the pleura: a case report. | Kragel and Wei Journal of Medical Case Reports 2011 5 248 http www.jmedicalcasereports.eom content 5 1 248 JOURNALOF medical case reports CASE REPORT Open Access Renal cell carcinoma metastasizing to solitary fibrous tumor of the pleura a case report Christopher Kragel and Shi Wei Abstract Introduction A tumor metastasizing to another malignancy is an uncommon phenomenon. Since it was first described in 1902 there have been fewer than 200 cases reported in the literature with lung cancer metastasizing to renal cell carcinoma being the most frequently described pattern. Here we report a case of a solitary fibrous tumor of the lung acting as the recipient for a renal cell carcinoma. To our knowledge this is the first reported case of such a combination and the second case involving a solitary fibrous tumor. Case presentation A 58-year-old Caucasian man who developed a persistent dry cough presented to our hospital. Imaging studies revealed a large pleural-based mass in the left lung. A biopsy of the mass showed a spindle-cell lesion consistent with a solitary fibrous tumor. The patient underwent surgical excision of the 13 cm mass. The pathological examination confirmed the diagnosis of a solitary fibrous tumor but also demonstrated discrete foci of metastatic renal cell carcinoma. Until that point a primary renal cell carcinoma tissue diagnosis had not been made and the initial radiological work-up was inconclusive. Conclusion Awareness of the unusual phenomenon of tumor-to-tumor metastasis is important for practicing surgical pathologists particularly in the evaluation of a mass lesion showing bimodal histology. This case also highlights the importance of careful examination of surgical specimens as minute and unusual findings can direct patient care. Introduction The coexistence of two primary neoplasms in one patient is not uncommon and these tumors may even arise at the same anatomic site collision tumor . However tumor-to-tumor metastasis is an extremely rare .