Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells

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Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells

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Human airway trypsin-like protease (HAT), a serine protease found in the sputum of patients with chronic airway diseases, is an agonist of protease-activated receptor-2 (PAR-2). Previous results have shown that HAT enhances the release of amphiregulin (AR); further, it causes MUC5AC gene expression through the AR-epidermal growth factor receptor pathway in the airway epithelial cell line NCI-H292.

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Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells

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Đang chuẩn bị liên kết để tải về tài liệu: Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells

Báo cáo y học: "Pneumocystis cell wall β-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells"

Báo cáo y học: " Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium"

Báo cáo y học: " A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged highthroughput biophysical screening"

Báo cáo y học: " The cytokine-driven regulation of secretoglobins in normal human upper airway and their expression, particularly that of uteroglobin-related protein 1, in chronic rhinosinusitis"

Báo cáo y học: " Real time analysis of b2-adrenoceptor-mediated signaling kinetics in Human Primary Airway Smooth Muscle Cells reveals both ligand and dose dependent differences"

Báo cáo y học: "Hepcidin expression in human airway epithelial cells is regulated by interferon-g"

Báo cáo y học: " Simvastatin inhibits TGFb1-induced fibronectin in human airway fibroblasts"

Báo cáo y học: " Mucin granule-associated proteins in human bronchial epithelial cells: the airway goblet cell “granulome”

Báo cáo y học: "IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13"

Báo cáo y học: " Nitric oxide gas phase release in human small airway epithelial cells"

Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells