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Chemical constituents of the rhizomes of Zingiber collinsii Mood &Theilade (zingiberaceae) growing in Vietnam

A chemical investigation of the rhizomes of Zingiber collinsii Mood & Theilade (Zingiberaceae) resulted in the isolation and identification of seven compounds, including a sesquiterpenoid (zerumbone(1)), acoumarin (scopoletin (2)), two flavonoids (quercetin (3), rutin (4)),afurfural derivative (5-(hydroxymethyl)furfural (5)), and two curcuminoids (bisdemethoxycurcumin (6),demethoxycurcumin (7)). The chemical structures of the seven compounds were determined on the basis of NMR and MS analyses. | Journal of Science and Technology 54 (4A) (2016) 283-289 CHEMICAL CONSTITUENTS OF THE RHIZOMES OF Zingiber collinsii Mood &Theilade (ZINGIBERACEAE) GROWING IN VIETNAM Le Thi My Chau1, 2, Vu Dinh Hoang3, Nguyen Thi Minh Tu2, *, Tran Dinh Thang1, * 1 Department of Chemistry, Vinh University, 182 Le Duan Street, Vinh City, Nghe An province 2 School of Biotechnology and Food Technology, Hanoi University of Science and Technology, 1 Dai Co Viet Street, Hai Ba Trung District, Hanoi 3 School of Chemical Engineering, Hanoi University of Science and Technology, 1 Dai Co Viet Street, Hai Ba Trung District, Hanoi * Email: tu.nguyenthiminh@hust.edu.vn, thangtd@vinhuni.edu.vn Received: 15 August 2016; Accepted for publication:7 October 2016 ABSTRACT A chemical investigation of the rhizomes of Zingiber collinsii Mood & Theilade (Zingiberaceae) resulted in the isolation and identification of seven compounds, including a sesquiterpenoid (zerumbone(1)), acoumarin (scopoletin (2)), two flavonoids (quercetin (3), rutin (4)),afurfural derivative (5-(hydroxymethyl)furfural (5)), and two curcuminoids (bisdemethoxycurcumin (6),demethoxycurcumin (7)). The chemical structures of the seven compounds were determined on the basis of NMR and MS analyses. Keywords:Zingiber collinsii, zerumbone, furfural, scopoletin, flavonoid, curcuminoid. 1. INTRODUCTION About 25 species of Zingiberaceae are used to cure multiple disorders in human and animals [1]. In addition to their medicinal activities, Zingiberaceae plants extracts may also serve as a natural larvicidal agent. Ginger extracts have anti-inflammatory, anti-oxidant and anticancer effects. Shogaol can significantly attenuate a variety of neuro inflammatory responses in cortical astrocytes [2,3]. Ginger supplementations significantly reduce severity of acute chemotherapy-induced nausea in adult cancer patients. The genus Zingiber Boehm has been represented by 13 species in Indo-China. Among them 10 species were reported from .