Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: "Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002. | Arthritis Research Vol 4 No 5 Falchetti Meeting report Genetics of osteoarticular disorders Florence Italy 22-23 February 2002 Alberto Falchetti Department of Internal Medicine University of Florence Florence Italy Corresponding author Alberto Falchetti e-mail a.falchetti@dmi.unifi.it Received 19 March 2002 Revisions received 17 May 2002 Accepted 28 June 2002 Published 30 July 2002 Arthritis Res 2002 4 326-331 2002 BioMed Central Ltd Print ISSN 1465-9905 Online ISSN 1465-9913 Abstract Osteoporosis OP and osteoarthritis OA the two most common age-related chronic disorders of articular joints and skeleton represent a major public health problem in most developed countries. They are influenced by environmental factors and exhibit a strong genetic component. Large population studies clearly show their inverse relationship therefore an accurate analysis of the genetic bases of one of these two diseases may provide data of interest for the other disorder. The discovery of risk and protective genes for OP and OA promises to revolutionize strategies for diagnosing and treating these disorders. The primary goal of this symposium was to bring together scientists and clinicians working on OP and OA in order to identify the most promising and collaborative approaches for the coming decade. This meeting put into focus the importance of an adequate genetic approach to several areas of research the search for the genetic determinants underlying new susceptibilities the optimization of previously acquired data the establishment of correlations between genetic polymorphism and functional variants and gene-gene and gene-environment interactions particularly those between genes and nutrients . An adequate genetic approach is also essential with regard to determining more selective criteria for phenotypic definition of familial OP in order to obtain more homogeneous and statistically powerful family-based studies. The symposium concluded with an interesting overview of the future .