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Báo cáo y học: "Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis. | Available online http arthritis-research.eom content 8 2 R40 Research article Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis Olivier Meyer1 Pascale Nicaise-Roland2 Marie dos Santos2 Colette Labarre2 Maxime Dougados3 Philippe Goupille4 Alain Cantagrel5 Jean Sibilia6 and Bernard Combe7 Rheumatology Unit Assistance Publique Hôpitaux de Paris Bichat University Hospital 75018 Paris France 2Biological Immunology Department Assistance Publique Hôpitaux de Paris Bichat University Hospital 75018 Paris France 3Rheumatology Unit B Assistance Publique Hôpitaux de Paris Cochin University Hospital 7501 4 Paris France 4Rheumatology Unit Trousseau University Hospital 37044 Tours Cedex 1 France 5Rheumatology Unit Rangueil University Hospital 31043 Toulouse Cedex 4 France 6Rheumatology Unit Hautepierre University Hospital 67098 Strasbourg Cedex France 7Rheumatology Unit Lapeyronie University Hospital 34296 Montpellier Cedex 5 France Corresponding author Olivier Meyer olivier.meyer@bch.aphp.fr Received 16 Sep 2005 Revisions requested 10 Oct 2005 Revisions received 12 Dec 2005 Accepted 4 Jan 2006 Published 26 Jan 2006 Arthritis Research Therapy 2006 8 R40 doi 10.1186 ar1 896 This article is online at http arthritis-research.com content 8 2 R40 2006 Meyer et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract The objective of this study was to evaluate the potential of serially determined anti-cyclic citrullinated peptide CCP antibodies for predicting structural joint damage in patients with early rheumatoid arthritis RA compared to a single baseline determination. Ninety-nine RA patients with .