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Báo cáo khoa học: "Quantitative assessment of inter-observer variability in target volume delineation on stereotactic radiotherapy treatment for pituitary adenoma and meningioma near optic tract"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Quantitative assessment of inter-observer variability in target volume delineation on stereotactic radiotherapy treatment for pituitary adenoma and meningioma near optic tract. | Yamazaki et al. Radiation Oncology 2011 6 10 http www.ro-journal.eom content 6 1 10 RADIATION ONCOLOGY RESEARCH Open Access Quantitative assessment of inter-observer variability in target volume delineation on stereotactic radiotherapy treatment for pituitary adenoma and meningioma near optic tract 1.2 28 1.2 1.2 1.2 1.2 Hideya Yamazaki Hiroya Shiomi Takuji Tsubokura Naohiro Kodani Takuya Nishimura Norihiro Aibe I_I I I- - I. I I I 1 fI 3 l A 1 1 1-4 II 4 7 S . r 1 1 I m I D -4 -4 5 K I Izi ZX -I 14 16 f I 1 1 I v . . 1 14 I 7 1 I Izi V 4 - r I I m -4 8 Hiroki Udono ivianabu Nishikata Yoshimi Baba Mikio Ogita Koichi Yamashita ladayuki Kotsuma Abstract Background To assess inter-observer variability in delineating target volume and organs at risk in benign tumor adjacent to optic tract as a quality assurance exercise. Methods We quantitatively analyzed 21 plans made by 11 clinicians in seven CyberKnife centers. The clinicians were provided with a raw data set pituitary adenoma and meningioma including clinical information and were asked to delineate the lesions and create a treatment plan. Their contouring and plans 10 adenoma and 11 meningioma plans were then compared. In addition we estimated the influence of differences in contouring by superimposing the respective contours onto a default plan. Results The median planning target volume PTV and the ratio of the largest to the smallest contoured volume were 9.22 cm3 range 7.17 - 14.3 cm3 and 1.99 for pituitary adenoma and 6.86 cm3 range 6.05 - 14.6 cm3 and 2.41 for meningioma. PTV volume was 10.1 1.74 cm3 for group 1 with a margin of 1 -2 mm around the CTV n 3 and 9.28 1.8 cm3 p 0.51 for group 2 with no margin n 7 in pituitary adenoma. In meningioma group 1 showed larger PTV volume 10.1 3.26 cm3 than group 2 6.91 0.7 cm3 p 0.03 . All submitted plan keep the irradiated dose to optic tract within the range of 50 Gy equivalent total doses in 2 Gy fractionation . However contours superimposed onto the dose distribution