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Báo cáo khoa học: "Survival rate in nasopharyngeal carcinoma improved by high caseload volume: a nationwide population-based study in Taiwan"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Survival rate in nasopharyngeal carcinoma improved by high caseload volume: a nationwide population-based study in Taiwan. | Lee et al. Radiation Oncology 2011 6 92 http www.ro-journal.eom content 6 1 92 RADIATION ONCOLOGY RESEARCH Open Access Survival rate in nasopharyngeal carcinoma improved by high caseload volume a nationwide population-based study in Taiwan c hiDH-f-hih I pp1 6 7 Ttp-To I Il IPDCI2 6 h lAAn- sinn I pp 3 5 6 Y11-Ckìipkì S1 I4 6 Ppqi IC Chr ii I7 shih-l lei IPP I Icipm1 6 Cliny dllll Lee Tze Id Hudny MUUH siny Lee lU Cliel sU rebus CHUU Slil HSUdll Hsido Wen-Yen Cliou3 6 Hon-Yi Lin3 6 Sou-Hsin Clien5 6 and Slil-Kdi Huny3 6 Abstract Background Positive correldtion between cdselodd dnd outcome lds previously been vdliddted for several procedures dnd cdncer tredtments. However tlere is no informdtion linking cdselodd dnd outcome of ndsopldrynyedl cdrcinomd NPC tredtment. We used ndtionwide populdtion-bdsed ddtd to exdmine tle dssocidtion between plysicidn cdse volume dnd survivdl rates of pdtients witl NPC. Methods Between 1998 dnd 2000 d totdl of 1225 pdtients were identified from tle Tdiwdn Ndtiondl Hedltl Insurance Resedrcl Ddtdbdse. Survivdl dndlysis tle Cox proportiondl ldZdrds model dnd propensity score were used to dssess tle reldtionslip between 10-yedr survivdl rates dnd plysicidn cdselodds. Results As tle cdselodd of individudl plysicidns incredsed unddjusted 10-yedr survivdl rates incredsed p 0.001 . Using d Cox proportiondl ldZdrd model pdtients witl NPC tredted by biyb-volume plysicidns cdselodd 35 ldd better survivdl rates p 0.001 dfter ddjustiny for comorbidities lospitdl dnd tredtment moddlity. Wlen dndlyzed by propensity score tle ddjusted 10-yedr survivdl rdte differed siynificdntly between pdtients tredted by liyl-volume plysicidns dnd pdtients tredted by low medium-volume plysicidns 75 vs. 61 p 0.001 . Conclusions Our ddtd confirm d positive volume-outcome reldtionslip for NPC. After ddjustiny for differences in tle cdse mix our dndlysis found tredtment of NPC by liyl-volume plysicidns improved 10-yedr survivdl rdte. Introduction The fact that .