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Báo cáo y học: "Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis | Available online http arthritis-research.eom content 9 1 R10 Open Access Research article Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis Susanne G Schad1 2 Andrea Kraus3 Imme Haubitz4 Jiri Trcka1 2 Henning Hamm1 and Hermann J Girschick3 1 Department of Dermatology Venereology and Allergology University of Wurzburg Josef-Schneider-Str 97080 Wurzburg Germany 2Department of Dermatology and Venereology University of Rostock Augustenstr 18055 Rostock Germany 3Department of Pediatrics Section of Pediatric Rheumatology and Osteology University of Wurzburg Josef Schneider Str 97080 Wurzburg Germany 4IT Centre University of Wurzburg Am Hubland 97074 Wurzburg Germany Corresponding author Susanne G Schad susanne.schaed@med.uni-rostock.de Received 11 Oct 2006 Revisions requested 1 Dec 2006 Revisions received 18 Jan 2007 Accepted 31 Jan 2007 Published 31 Jan 2007 Arthritis Research Therapy 2007 9 R10 doi 10.1186 ar2117 This article is online at http arthritis-research.com content 9 1 R10 2007 Schad et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Pseudoporphyria PP is characterized by skin fragility blistering and scarring in sun-exposed skin areas without abnormalities in porphyrin metabolism. The phenylpropionic acid derivative group of nonsteroidal anti-inflammatory drugs especially naproxen is known to cause PP. Naproxen is currently one of the most prescribed drugs in the therapy of juvenile idiopathic arthritis JIA . The prevalence of PP was determined in a 9-year retrospective study of children with JIA and associated diseases. In addition we prospectively studied the incidence of PP in 196 patients 127 girls and 69 boys with JIA .

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Báo cáo y học: "Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis"

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