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Báo cáo y học: "Inhibition of breathing after surfactant depletion is achieved at a higher arterial PCO2 during ventilation with liquid than with gas"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Inhibition of breathing after surfactant depletion is achieved at a higher arterial PCO2 during ventilation with liquid than with gas. | Respiratory Research BioMed Central Research Open Access Inhibition of breathing after surfactant depletion is achieved at a higher arterial PCO2 during ventilation with liquid than with gas Esther Rieger-Fackeldey 1 2 3 Richard Sindelar1 2 Anders Jonzon1 2 Andreas Schulze3 and Gunnar Sedin1 2 Address Department of Women s and Children s Health Section for Pediatrics Uppsala University Uppsala Sweden 2Department of Neuroscience Division of Physiology Uppsala University Uppsala Sweden and 3Department of Obstetrics and Gynecology Division of Neonatology Klinikum Grosshadern Ludwig Maximilian University Munich Germany Email Esther Rieger-Fackeldey - esther.fackeldey@kbh.uu.se Richard Sindelar - richard.sindelar@kbh.uu.se Anders Jonzon - anders.jonzon@akademiska.se Andreas Schulze - andreas.schulze@med.uni-muenchen.de Gunnar Sedin - gunnar.sedin@kbh.uu.se Corresponding author Published 04 March 2005 Received 23 December 2004 Respiratory Research 2005 6 24 doi 10.1186 1465-9921 -6-24 Accepted 04 March 2005 This article is available from http respiratory-research.cOm content 6 1 24 2005 Rieger-Fackeldey et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Inhibition of phrenic nerve activity PNA can be achieved when alveolar ventilation is adequate and when stretching of lung tissue stimulates mechanoreceptors to inhibit inspiratory activity. During mechanical ventilation under different lung conditions inhibition of PNA can provide a physiological setting at which ventilatory parameters can be compared and related to arterial blood gases and pH. Objective To study lung mechanics and gas exchange at inhibition of PNA during controlled gas ventilation GV and during partial liquid ventilation PLV before and .