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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury. | Available online http ccforum.eom content 8 2 115 Review Clinical review The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury Enrique Piacentini1 Ana Villagrá2 Josefina Lopez-Aguilar3 and Lluis Blanch4 Research Fellow Critical Care Centre Hospital de Sabadell Institut Universitari Parc Taulí Universitat Autònoma de Barcelona Sabadell Spain 2Research Fellow Critical Care Centre Hospital de Sabadell Institut Universitari Parc Taulí Universitat Autònoma de Barcelona Sabadell Spain 3Researcher Critical Care Centre Hospital de Sabadell Institut Universitari Parc Taulí Universitat Autònoma de Barcelona Sabadell Spain 4Executive Director Critical Care Centre Hospital de Sabadell Institut Universitari Parc Taulí Universitat Autònoma de Barcelona Sabadell Spain Correspondence Lluis Blanch lblanch@cspt.es Published online 5 September 2003 Critical Care 2004 8 115-121 DOI 10.1186 cc2364 This article is online at http ccforum.com content 8 2 115 2004 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Mechanical ventilation can cause and perpetuate lung injury if alveolar overdistension cyclic collapse and reopening of alveolar units occur. The use of low tidal volume and limited airway pressure has improved survival in patients with acute lung injury or acute respiratory distress syndrome. The use of recruitment maneuvers has been proposed as an adjunct to mechanical ventilation to re-expand collapsed lung tissue. Many investigators have studied the benefits of recruitment maneuvers in healthy anesthetized patients and in patients ventilated with low positive end-expiratory pressure. However it is unclear whether recruitment maneuvers are useful when patients with acute lung injury or acute respiratory distress syndrome are ventilated with high positive end-expiratory pressure and in the presence of lung fibrosis or a stiff chest wall. Moreover it is unclear whether the use of high airway pressures during .