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Báo cáo khoa học: "Myocardial infarction complicating critical illness"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Myocardial infarction complicating critical illness. | Critical Care December 2005 Vol 9 No 6 King and Almog Commentary Myocardial infarction complicating critical illness Daniel A King1 and Yaniv Almog2 1 Fellow Division of Pulmonary and Critical Care Medicine University of Maryland Medical Center Baltimore MD USA 2Director Medical Intensive Care Unit Soroka University Medical Center Beer-Sheva Israel Corresponding author Yaniv Almog almogya@bgu.ac.il Published online 2 November 2005 This article is online at http ccforum.com content 9 6 634 2005 BioMed Central Ltd Critical Care 2005 9 634-635 DOI 10.1186 cc3893 See related research by Lim et al. in this issue http ccforum.com content 9 6 R636 Abstract Cardiac troponins are highly sensitive and specific indicators of myocardial injury. Although the mechanism of this injury is not entirely clear it carries important prognostic information. Elevated serum levels of cardiac troponins have been described in a wide variety of conditions other than myocardial infarction MI . The current study is an important first step in trying to determine the exact frequency of MI among critically ill patients with elevated troponin. At present the rate of MI in these patients is unknown and its implications on outcome and management will have to await future prospective clinical trials. In this issue of Critical Care Lim and colleagues examine the frequency of myocardial infarction MI among a non-selected group of critically ill patients 1 . Cardiac troponins I cTnI and T myocardial regulatory proteins of the thin actin filament are considered highly sensitive and specific indicators of myocardial injury. Over the past decade measuring cardiac troponin levels has become the corner stone of detecting myocardial injury to the extent that it is now an inseparable part of the current guidelines for diagnosis and management of acute coronary syndromes ACS and MI 2 . It is well established that reasons other than thrombotic MI can cause elevated serum levels of cardiac troponins 3 4 . Such .