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Báo cáo y học: "Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral™ index monitor"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral™ index monitor. | Available online http ccforum.eom content 11 5 R108 Research Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral index monitor Sandra A Prins1 Matthijs de Hoog2 Joleen H Blok3 Dick Tibboel1 and Gerhard H Visser3 department of Pediatric Surgery Intensive Care Unit Erasmus MC University Medical Center Sophia Children s Hospital Dr. Molewaterplein 60 3015 GJ Rotterdam The Netherlands department of Pediatrics Intensive Care Unit Erasmus MC University Medical Center Sophia Children s Hospital Dr. Molewaterplein 60 3015 GJ Rotterdam The Netherlands department of Clinical Neurophysiology Erasmus MC University Medical Center s Gravendijkwal 230 3015 CE Rotterdam the Netherlands Corresponding author DickTibboel d.tibboel@erasmusmc.nl Received 9 Jan 2007 Revisions requested 22 Feb 2007 Revisions received 16 Jul 2007 Accepted 27 Sep 2007 Published 27 Sep 2007 Critical Care 2007 11 R108 doi 10.1186 cc6138 This article is online at http ccforum.com content 11 5 R1 08 2007 Prins et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Traumatic brain injury and generalized convulsive status epilepticus GCSE are conditions that require aggressive management. Barbiturates are used to lower intracranial pressure or to stop epileptiform activity with the aim being to improve neurological outcome. Dosing of barbiturates is usually guided by the extent of induced burst-suppression pattern on the electroencephalogram EEG . Dosing beyond the point of burst suppression may increase the risk for complications without offering further therapeutic benefit. For this reason careful monitoring of EEG parameters is mandatory. A prospective study was conducted to evaluate .