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Báo cáo y học: "The assessment of quality of life in acute cough with the Leicester"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The assessment of quality of life in acute cough with the Leicester Cough Questionnaire (LCQ-acute). | Yousaf et al. Cough 2011 7 4 http www.coughjournal.eom content 7 1 4 Cough RESEARCH Open Access The assessment of quality of life in acute cough with the Leicester Cough Questionnaire LCQ-acute Nadia Yousaf1 Kai K Lee2 Bhagyashree Jayaraman2 Ian D Pavord1 and Surinder S Birring2 Abstract Introduction Acute cough has a significant impact on physical and psychosocial health and is associated with an impaired quality of life QOL . The Leicester Cough Questionnaire LCQ is a validated cough-related health status questionnaire designed for patients with chronic cough. The purpose of this study was to validate the LCQ for the assessment of health related QOL in patients with acute cough and determine the clinical minimal important difference MID . Methods 10 subjects with cough due to acute upper respiratory tract infection underwent focused interviews to investigate the face validity of the LCQ. The LCQ was also evaluated by a multidisciplinary team. 30 subjects completed the revised LCQ-acute and a cough visual analogue score VAS 0-100 mm within one week of onset of cough and again 2 weeks later and at resolution of cough. The concurrent validity internal reliability repeatability and responsiveness of the LCQ-acute were also assessed. Patients also completed a Global Rating of Change Questionnaire that assessed the change in cough severity between visits. The MID was calculated as the change in LCQ-acute score for patients responding to GRCQ category representing the smallest change in health status that patients found worthwhile. Results Health status was severely impaired at baseline affecting all domains median interquartile range total LCQ-acute score 13.0 3.4 . All subjects found the LCQ-acute questionnaire acceptable for assessing their cough. Internal reliability of the LCQ-acute was good for all domains and total score Cronbach s a coefficients 0.9. There was a significant correlation between LCQ-acute and VAS p -0.48 p 0.007 . The LCQ-acute and its domains .