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Báo cáo y học: "Mobile DNA: genomes under the influence"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Mobile DNA: genomes under the influence. | Meeting report Mobile DNA genomes under the influence Cédric Feschotte and Ellen J Pritham Address Department of Biology University of Texas at Arlington TX 76019 USA. Correspondence Cédric Feschotte. Email cedric@uta.edu Published 30 June 2006 Genome Biology 2006 7 320 doi l0.ll86 gb-2006-7-6-320 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2006 7 6 320 2006 BioMed Central Ltd A report on the American Society for Microbiology Conference on Mobile DNA Banff Canada 24 February-1 March 2006. Mobile DNA is a relatively loose term that encompasses an amazing diversity of genetic elements that are capable of movement from one genomic locale to another and can often invade other genomes. Transposable elements transposons among the most widespread forms of mobile DNA populate the genomes of most living organisms and have propagated to enormous numbers in many eukaryotes for example about half of the human genome is directly derived from transposable elements . An understanding of the behavior of transposable elements is therefore essential to our understanding of how genomes function and evolve. A recent conference on mobile DNA provided many outstanding examples of research in this rich and vibrant field a few of which are highlighted here. We focus on work that advances our understanding of the impact of transposable elements on the evolutionary trajectories of their host genomes. The influence of transposable elements on genome structure With the advent of genomics the significant influence of transposable elements in shaping the genomes of virtually all organisms is becoming fully appreciated. Most of the transposable elements in mammalian genomes are retro-transposons transposable elements that transpose via an RNA intermediate. More than a million copies of the Alu retrotransposon occur scattered throughout the human genome. Mark Batzer Louisiana State University Baton Rouge USA reported work showing .