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Báo cáo y học: " Immune Restoration Syndrome with disseminated Penicillium marneffei and Cytomegalovirus co-infections in an AIDS patient"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Immune Restoration Syndrome with disseminated Penicillium marneffei and Cytomegalovirus co-infections in an AIDS patient. | AIDS Research and Therapy BioMed Central Case report Open Access Immune Restoration Syndrome with disseminated Penicillium marneffei and Cytomegalovirus co-infections in an AIDS patient Swati Gupta1 Purva Mathur1 Dipesh Maskey2 Naveet Wig2 and Sarman Singh 1 Address 1Division of Clinical Microbiology Department of Laboratory Medicine All India Institute of Medical Sciences New Delhi 110029 India and 2Department of Internal Medicine All India Institute of Medical Sciences New Delhi 110029 India Email Swati Gupta - swatgan@yahoo.com Purva Mathur - purvamathur@yahoo.co.in Dipesh Maskey - dipesh_aiims@yahoo.com Naveet Wig - naveet_wig@yahoo.com Sarman Singh - sarman_singh@yahoo.com Corresponding author Published 8 October 2007 Received 14 July 2007 AIDS Research and Therapy 2007 4 21 doi 10.1186 1742-6405-4-21 Accepted 8 October 2007 This article is available from http www.aidsrestherapy.com content 4 1 21 2007 Gupta et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Penicillium marneffei is a dimorphic fungus endemic in South-east Asia. The fungus causes severe disease in immunocompromised patients such as AIDS. However no case of immune restoration disease of Penicillium marneffei is reported in literature from a non-endemic area. Case Presentation We report the first case of Penicillium marneffei and Cytomegalovirus infection manifesting as a result of immune restoration one month after initiating HAART. This severely immunocompromised patient had presented with multiple lymphadenopathy massive hepatosplenomegaly visual impairment and mild icterus but no skin lesions. Penicillium marneffei was isolated from lymph node fine-needle aspirates and blood cultures. Conclusion In order to diagnose such rare .