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Báo cáo y học: "Association between thymoma and persistent hypothermia: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Association between thymoma and persistent hypothermia: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Association between thymoma and persistent hypothermia a case report Robin H Johns and Alistair K Reinhardt Address Chest Clinic Whipps Cross University Hospital NHS Trust London E11 1NR UK Email Robin H Johns - drrobinhjohns@hotmail.com Alistair K Reinhardt - alistair.reinhardt@whippsx.nhs.uk Corresponding author Published 12 October 2009 Received 12 October 2009 Journal of Medical Case Reports 2009 3 73 doi l0.ll86 l752-l 947-3-73 Accepted 12 October 2009 This article is available from http www.jmedicalcasereports.com content 3 1 73 2009 Johns and Reinhardt licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Thymomas are rare slow-growing tumours that present in a variety of ways such as incidental findings on chest radiographs following symptoms of cough and dyspnoea. Thymomas may also present with symptoms due to intrathoracic spread such as superior vena cava obstruction or with symptoms of an associated paraneoplastic disorder. Such paraneoplastic disorders are typified by the generation of autoantibodies directed against a variety of self antigens including myasthenia gravis neuromyotonia and hypogammaglobulinaemia. Significant hypothermia in association with thymoma has been described previously in one published case report. The basis for hypothermia in that case was not clear but was postulated to relate to abnormal central thermal regulation and was resolved completely following treatment with intravenous gammablobulin thus suggesting an autoimmune aetiology. Case presentation We present the case of an 88-year-old man with Type A thymoma and persistent hypothermia. An extensive investigation of the hypothermia revealed no .