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báo cáo hóa học:" Human embryonic stem cells hemangioblast express HLA-antigens"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Human embryonic stem cells hemangioblast express HLA-antigens | Journal of Translational Medicine BioMed Central Open Access Human embryonic stem cells hemangioblast express HLA-antigens Grzegorz Wladyslaw Basak11 2 Satoshi Yasukawa11 Andre Alfaro1 Samantha Halligan1 Anand S Srivastava3 Wei-Ping Min4 Boris Minev1 and Ewa Carrier 1 Address 1Rebecca and John Moore s Cancer Center University of California San Diego La Jolla CA 92093 USA 2Department of Hematology Oncology and Internal Diseases The Medical University of Warsaw Warsaw 02-097 Poland 3Salk Institute Department of Stem Cells La Jolla CA 92093 USA and departments of Surgery Microbiology Immunology Pathology University of Western Ontario London Ontario N6A 5A5 Canada Email Grzegorz Wladyslaw Basak - gbasak@ib.amwaw.edu.pl Satoshi Yasukawa - yasukawa-satoshi@jpo.go.jp Andre Alfaro - aj_alfaro4@yahoo.com Samantha Halligan - srhalliga@aol.com Anand S Srivastava - sanand18@hotmail.com Wei- Ping Min - mweiping@uwo.ca Boris Minev-bminev@ucsd.edu Ewa Carrier - ecarrier@ucsd.edu Corresponding author fEqual contributors Published 22 April 2009 Received 3 December 2008 Journal of Translational Medicine 2009 7 27 doi 10.1186 1479-5876-7-27 Accepted 22 April 2009 This article is available from http www.translational-medicine.cOm content 7 1 27 2009 Basak et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background It has been suggested that the initial differentiation of endothelial and hematopoietic cells during embryogenesis occurs from a common progenitor called hemangioblast hB . We hypothesized that these cells with dual hematopoietic endothelial potential could be used in future regenerative medicine. Methods We used the two-step differentiation technology to generate bipotential blast cells from human embryonic stem cells