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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"

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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia. | Int. J. Med. Sci. 2011 8 30 Research Paper International Journal of Medical Sciences 2011 8 1 30-38 Ivyspring International Publisher. All rights reserved. Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia Songul Serefhanoglu H Yahya Buyukasik Hakan Emmungil Nilgun Sayinalp Ibrahim Celalettin Hazne-daroglu Hakan Goker Salih Aksu Osman Ilhami Ozcebe Hacettepe University Hospital Department of Internal Medicine Division of Hematology Ankara Turkey H Corresponding author Songul Serefhanoglu Hacettepe University Hospital Department of Internal Medicine Division of Hematology Ankara Turkey. E-mail dr.songul1978@yahoo.com Tlf 903123051543. Received 2010.08.29 Accepted 2010.12.20 Published 2010.12.28 Abstract Iron deficiency anemia IDA is a frequent disorder. Also it may be a sign of underlying serious diseases. Iron deficiency points to an occult or frank bleeding lesion when occurred in men or postmenopausal women. In this study we aimed to evaluate the diagnostic yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal GI lesions causing IDA. Ninety-one patients 77 women 14 men mean age 43 years who were decided to have esophago-duodenoscopy and or colonoscopy for iron deficiency anemia were interviewed and responded to a questionnaire that included clinical and biochemical variables. The endoscopic findings were recorded as GI lesions causing IDA or not causing IDA. Endoscopy revealed a source of IDA in 18.6 of cases. The risk factors for finding GI lesions causing IDA were as follows male gender p 0.004 advanced age 50 years p 0.010 weight loss over 20 of total body weight lost in last 6 month p 0.020 chronic diarrhea p 0.006 change of bowel habits p 0.043 epigastric tenderness p 0.037 raised carcinoembryonic antigen CEA level normal range 0-7 ng mL p 0.039 10 gr dl hemoglobin Hb level p 0.054 . None of these risk factors had been .

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