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Báo cáo y học: "Lack of Preemptive Analgesia by Intravenous Flurbiprofen in Thyroid Gland Surgery: A Randomized, Double-blind and Placebo-controlled Clinical Trial"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Lack of Preemptive Analgesia by Intravenous Flurbiprofen in Thyroid Gland Surgery: A Randomized, Double-blind and Placebo-controlled Clinical Trial. | Int. J. Med. Sci. 2011 8 433 o IVYSPRING KIBTOTOWRU L . International Journal of Medical Sciences 2011 8 5 433-438 Research Paper Lack of Preemptive Analgesia by Intravenous Flurbiprofen in Thyroid Gland Surgery A Randomized Double-blind and Placebo-controlled Clinical Trial Zhaodi Zhang1 Haifang Zhao1 Changsong Wang2 Fei Han1 Guonian Wang1 x 1. Department of Anesthesiology the Third Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150081 China. 2. Department of Anesthesiology the First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China Zhaodi Zhang and Haifang Zhao contributed equally to this work. H Corresponding author Prof. Guonian Wang Department of Anesthesiology the Third Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150081 China. Fax 86-0451-86298811 Email wangguonian609cn@yahoo.com.cn Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License http creativecommons.org licenses by-nc-nd 3.0 . Reproduction is permitted for personal noncommercial use provided that the article is in whole unmodified and properly cited. Received 2011.03.28 Accepted 2011.07.07 Published 2011.07.15 Abstract Background Nowadays increasingly more preemptive analgesia studies focus on postoperative pain however the impact of preemptive analgesia on perioperative opioid requirement is not well defined. This study was carried out in order to evaluate whether preoperative intravenous flurbiprofen axetil can reduce perioperative opioid consumption and provide postoperative analgesia in patients undergoing thyroid gland surgery. Methods Ninety patients undergoing elective thyroid gland surgery were randomly assigned to three groups. Group A Control was administered Intralipid 2 ml as a placebo 15 min before the cervical plexus block and at the end of the surgery Group B Routine analgesia was administered a placebo 15 min before the cervical plexus .