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Báo cáo y học: "Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study. | Annals of General Psychiatry BioMed Central Primary research Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan a retrospective cohort study Syed Ahmer 1 Rashid AM Khan1 and Saleem Perwaiz Iqbal2 Open Access Address Department of Psychiatry Aga Khan University Karachi Pakistan and 2Department of Paediatrics Child Health Aga Khan University Karachi Pakistan Email Syed Ahmer - syed.ahmer@aku.edu Rashid AM Khan - rashid.masud@aku.edu Saleem Perwaiz Iqbal - saleem.iqbal@aku.edu Corresponding author Published 18 August 2008 Received II March 2008 Annals of General Psychiatry 2008 7 12 doi 10.1186 1744-859X-7-12 Accepted 18 August 2008 This article is available from http www.annals-general-psychiatry.com content 7 I I2 2008 Ahmer et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background It has been known for a long time that use of antipsychotics particularly atypical antipsychotics is associated with weight gain and increase in risk of metabolic disturbances. In this study we have tried to find out if use of antipsychotics is associated with increase in weight and body mass index BMI in the Pakistani population. Methods We performed a case note review of all patients who had been prescribed antipsychotic medication at the psychiatry outpatient clinic of a tertiary care university hospital in Pakistan over a 4-year period. Results A total of 50 of patients had a BMI in the overweight or higher range at baseline. Patients showed a mean weight gain of 1.88 kg from baseline in 3 months and 3.29 kg in 6 months. Both of these values were statistically significant. The increase in mean BMI from baseline was 0.74 and 1.3 in 3 months and 6 months respectively. In patients for whom