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Báo cáo y học: " Bacterial activity in cystic fibrosis lung infections"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Bacterial activity in cystic fibrosis lung infections. | Respiratory Research BioMed Central Research Open Access Bacterial activity in cystic fibrosis lung infections Geraint B Rogers1 2 Mary P Carroll2 David J Serisier2 4 Peter M Hockey2 Valia Kehagia2 Graeme R Jones3 and Kenneth D Bruce 1 Address Department of Life Sciences King s College London London UK 2Cystic Fibrosis Unit Southampton University Hospitals NHS Trust UK 3Health Protection Agency Southampton Laboratory UK and 4The Adult Cystic Fibrosis Unit Mater Adult Hospital Brisbane Australia Email Geraint B Rogers - geraint.rogers@kcl.ac.uk Mary P Carroll - mary@cjwing.demon.co.uk David J Serisier - David_Serisier@mater.org.au Peter M Hockey - Peter.Hockey@pulmonology.co.uk Valia Kehagia - valkeh@yahoo.com Graeme R Jones - Graeme.Jones@suht.swest.nhs.uk Kenneth D Bruce - kenneth.bruce@kcl.ac.uk Corresponding author Published 01 June 2005 Received 27 August 2004 Respiratory Research 2005 6 49 doi l0.ll86 l465-992l-6-49 Accepted 0I June 2005 This article is available from http respiratory-research.cOm content 6 l 49 2005 Rogers et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Chronic lung infections are the primary cause of morbidity and mortality in Cystic Fibrosis CF patients. Recent molecular biological based studies have identified a surprisingly wide range of hitherto unreported bacterial species in the lungs of CF patients. The aim of this study was to determine whether the species present were active and as such worthy of further investigation as potential pathogens. Methods Terminal Restriction Fragment Length Polymorphism T-RFLP profiles were generated from PCR products amplified from l6S rDNA and Reverse Transcription Terminal Restriction Fragment Length Polymorphism RT-T-RFLP profiles a

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