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Báo cáo y học: " Endothelial Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Endothelial Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study. | Magret et al. Critical Care 2011 15 R62 http ccforum.eom content 15 1 R62 KS CRITICAL CARE RESEARCH Open Access Bacteremia is an independent risk factor for mortality in nosocomial pneumonia a prospective and observational multicenter study K IAf iir Ti K l nrot 1 TF1 i Z 1 ni I icHr iT 2 I 1 K i rHn-l r lOf hoc3 K i rSo- 4 Mm HAA nolz5 I IcirmTif if i A rinno6 Mònicd Mdyrei iiiidyo Lisbod Iyndcio Mditiii Loeciies Rdfdel Manez Mdrc iNduvvynck Hieiiiidiin vviiyye Silvano Cdrdellino7 Emili Didz2 Despind Koulenti8 dnd Jordi Rello9 for EU-VAP CAP Study Group Abstract Introduction Since positive blood cultures die uncommon in pdtients with nosocomidl pneumonid NP the responsible pdthoyens dre usudlly isoldted from respiratory sdmples. Studies on bdcteremid dssocidted with hospitdl-dcquired pneumonid HAP hdve reported fdtdlity rates of up to 50 . The purpose of the study is to compdre risk fdctors pdthoyens dnd outcomes between bdcteremic nosocomidl pneumonid B-NP dnd nonbdcteremic nosocomidl pneumonid NB-NP episodes. Methods This is d prospective observdtiondl dnd multicenter study 27 intensive cdre units in nine Europedn countries . Consecutive pdtients requiriny invdsive mechdnicdl ventildtion for dn ddmission didynosis of pneumonid or on mechdnicdl ventildtion for 48 hours irrespective of ddmission didynosis were recruited. Results A totdl of 2 436 pdtients were evdludted 689 intubdted pdtients presented with NP 224 of them developed HAP dnd 465 developed ventildtion-dcquired pneumonid. Blood sdmples were extracted in 479 69.5 pdtients 70 14.6 beiny positive. B-NP pdtients hdd hiyher Simplified Acute Physioloyy Score SAPS II score 51.5 19.8 vs. 46.6 17.5 P 0.03 dnd were more frequently medicdl pdtients 77.1 vs. 60.4 P 0.01 . Mortdlity in the intensive cdre unit wds hiyher in B-NP pdtients compdred with NB-NP pdtients 57.1 vs. 33 P 0.001 . B-NP pdtients hdd d more prolonyed medn intensive cdre unit lenyth of stdy dfter pneumonid onset thdn NB-NP pdtients 28.5 30.6 vs.