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báo cáo khoa học: " Hypothyroidism in a five-year-old boy with rhabdomyolysis and recent history of cardiac tamponade: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Hypothyroidism in a five-year-old boy with rhabdomyolysis and recent history of cardiac tamponade: a case report | Delgado Hurtado et al. Journal of Medical Case Reports 2011 5 515 http www.jmedicalcasereports.eom content 5 1 515 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Hypothyroidism in a five-year-old boy with rhabdomyolysis and recent history of cardiac tamponade a case report 1 2 2 2 2 Juan José Delgado Hurtado Waleska Guevara Evelyn Ramos Claudia Lorenzana and Susana Soto Abstract Introduction Cardiac tamponade is a rare manifestation of hypothyroidism and a less rare cause of pericardial effusion. The accumulation of the pericardial fluid is gradual and often does not compromise cardiac hemodynamic function. There is a relationship between the severity and chronicity of the disease with the presence of pericardial effusion. There are few cases describing associated pericardial tamponade published in the literature. When a tamponade occurs a concomitant provocative factor such as a viral pericarditis may be related. Our patient s case appears to be the youngest patient described so far. Case presentation We report the case of a previously healthy five-year-old Hispanic non-indigenous boy who developed rhabdomyolysis with a history of a recent pericardial effusion and tamponade two months before that required the placement of a percutaneous pericardial drainage. Pericardial effusion was considered to be viral. Later on readmission clinical primary hypothyroidism was diagnosed and thought to be associated with the previous cardiac tamponade. He developed rhabdomyolysis which was considered to be autoimmune and was treated with steroids. The level of creatine phosphate kinase and creatine kinase MB fraction returned to within the reference rangeone week after our patient was started on steroids and three weeks after he was started on thyroid hormones. Conclusions Physicians should consider hypothyroidism as a differential diagnosis in patients with pericardial effusion. Pericardial effusion may progress and cause a cardiac tamponade with hemodynamic .