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Báo cáo y học: "Characterization of subcellular localization of duck enteritis virus UL51 protein"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Characterization of subcellular localization of duck enteritis virus UL51 protein | BioMed Central Virology Journal Research Characterization of subcellular localization of duck enteritis virus UL51 protein Chanjuan Shen11 Yufei Guo11 Anchun Cheng 11 2 Mingshu Wang11 2 Yi Zhou1 Dan Lin1 Hongyi Xin1 and Na Zhang1 Address 1Avian Diseases Research Center College of Veterinary Medicine of Sichuan Agricultural University Ya an Sichuan 625014 PR China and 2Key Laboratory of Animal Diseases and Human Health of Sichuan Province Ya an Sichuan 625014 PR China Email Chanjuan Shen - vorber@163.com Yufei Guo - gyf02@163.com Anchun Cheng - chenganchun@vip.163.com Mingshu Wang - mshwang@163.com Yi Zhou - cchng02@163.com Dan Lin - lindan0107@163.com Hongyi Xin - hongyi_xin@163.com Na Zhang - nana821024@sohu.com Corresponding author fEqual contributors Open Access Published 3 July 2009 Received 13 May 2009 Virology Journal 2009 6 92 doi 10.1186 1743-422X-6-92 Accepted 3 July 2009 This article is available from http www.virologyj.cOm content 6 1 92 2009 Shen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Knowledge of the subcellular localization of a protein can provide useful insights about its function. While the subcellular localization of many alphaherpesvirus UL51 proteins has been well characterized little is known about where duck enteritis virus DEV UL51 protein pUL51 is targeted to. Thus in this study we investigated the subcellular localization and distribution of DEV pUL51 by computer aided analysis as well as indirect immunofluorescence IIF and transmission immunoelectron microscopy TIEM approaches in DEV-infected cells. Results The DEV UL51 gene product was identified as an approximate 34 kDa protein in .