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báo cáo hóa học: " Persistently elevated T cell interferon-γ responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Persistently elevated T cell interferon-γ responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report | Journal of Occupational Medicine and Toxicology BioMed Central Research Open Access Persistently elevated T cell interferon-Y responses after treatment for latent tuberculosis infection among health care workers in India a preliminary report Madhukar Pai 1 2 3 Rajnish Joshi1 2 Sandeep Dogra2 Deepak K Mendiratta2 Pratibha Narang2 Keertan Dheda4 and Shriprakash Kalantri2 Address 1Division of Epidemiology School of Public Health University of California Berkeley USA 2Departments of Medicine Microbiology Mahatma Gandhi Institute of Medical Sciences Sevagram India 3Division of Pulmonary Critical Care Medicine San Francisco General Hospital University of California San Francisco USA and 4Centre for Infectious Diseases and International Health The Royal Free and University College Medical School London UK Email Madhukar Pai - madhupai@berkeley.edu Rajnish Joshi - rjoshimgims@gmail.com Sandeep Dogra - sandy1412@yahoo.com Deepak K Mendiratta - dkmendiratta@rediffmail.com Pratibha Narang - deanmgi@rediffmail.com Keertan Dheda - keertandheda@yahoo.co.uk Shriprakash Kalantri - sp.kalantri@gmail.com Corresponding author Published 23 May 2006 Received 10 February 2006 Journal of Occupational Medicine and Toxicology 2006 1 7 doi l0.ll 86 1745-6673-1-7 Accepted 23 May 2006 This article is available from http www.occup-med.cOm content 1 1 7 2006 Pai et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background T cell-based interferon-Y IFN-y release assays IGRAs are novel tests for latent tuberculosis infection LTBI . It has been suggested that T cell responses may be correlated with bacterial burden and therefore IGRAs may have a role in monitoring treatment response. We investigated IFN-Y responses to specific TB antigens .