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báo cáo khoa học: "Inflammatory pseudo-tumor of the liver: a rare pathological entity"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Inflammatory pseudo-tumor of the liver: a rare pathological entity | Faraj et al. World Journal of Surgical Oncology 2011 9 5 http www.wjso.eom content 9 1 5 WORLD JOURNAL OF SURGICAL ONCOLOGY REVIEW Open Access Inflammatory pseudo-tumor of the liver a rare pathological entity Walid Faraj Hana Ajouz Deborah Mukherji Gerald Kealy Ali Shamseddine Mohamed Khalife Abstract Inflammatory pseudo-tumor IPT of the liver is a rare benign neoplasm and is often mistaken as a malignant entity. Few cases have been reported in the literature and the precise etiology of inflammatory pseudotumor remains unknown. Patients usually present with fever abdominal pain and jaundice. The proliferation of spindled myofibroblast cells mixed with variable amounts of reactive inflammatory cells is characteristics of IPT. We reviewed the literature regarding possible etiology for IPT with a possible suggested etiology. Introduction Inflammatory pseudo-tumor IPT of the liver is a rare benign neoplasm and is often mistaken as a malignant entity. They were first described in the lung in 1939 and have been reported subsequently in numerous locations including the liver spleen lymph nodes spinal cord salivary glands breast and soft tissues. Liver involvement was first described in 1953 by Pack and Baker and may lead to biliary obstruction portal hypertension cirrhosis and eventually hepatic failure. Few cases have been reported in the literature with no recognized etiology for IPT 1-4 . Patients usually present with fever abdominal pain and jaundice. The proliferation of spindled myofibroblast cells mixed with variable amounts of reactive inflammatory cells is characteristic of IPT. IPT is sometimes misdiagnosed as a malignant tumor based on radiographic findings. We reviewed the literature regarding possible etiology for IPT with a possible suggested etiology. Exaggerated Inflammatory response Inflammatory pseudotumour IPT of the liver also known as inflammatory myofibroblastic tumor is a rare benign condition which has been diagnosed with increasing frequency .