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báo cáo khoa học: "Aspergilloma in combination with adenocarcinoma of the lung"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Aspergilloma in combination with adenocarcinoma of the lung | Smahi et al. World Journal of Surgical Oncology 2011 9 27 http www.wjso.eom content 9 1 27 7 2 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Aspergilloma in combination with adenocarcinoma of the lung 1 2 I 1 3 3 3 Mohamed Smahi Mounia Serraj Yassine Ouadnouni Laila Chbani Kaoutar Znati Afaf Amarti Abstract A 60 year old male with a long standing history of smoking was referred to our department for surgery of aspergilloma in right upper lung lobe diagnosed by computed tomography and confirmed by computed tomography guided needle aspiration biopsy. A lobectomy was performed. Histological study of the surgical specimen revealed a pulmonary adenocarcinoma associated with aspergilloma. By presenting this case we suggest that every case of pulmonary aspergillome should be examined for malignancies especially in smokers. In Morocco pulmonary aspergilloma is most commonly diagnosed in a patient with a healed tuberculous cavity. It rarely affects healthy people with an intact immune response but those with preexisting structural lung disease atopy occupational exposure or impaired immunity are susceptible. Aspergillosis can remain asymptomatic or present with hemoptysis which can be life-threatening 1 . In this report we describe a fortuitous discovery of unsuspected lung adenocarcinoma in surgical resection performed for aspergilloma of the right upper lobe. Case A 60 -year-old man with social history included a 25 packs year smoking habit who was otherwise healthy presented with history of cough productive with some episodes of small hemoptysis for 7 weeks. There was no history of chest pain shortness of breath fever or chills and he denied any history of weight loss. On physical examination he appeared healthy with normal findings. Chest radiography revealed a cavitary lesion with air crescent sign characteristic of an intracavitary mycetoma Figure 1 and on CT there was a cavitary lesion on horseback on the segments of the right upper lung lobe with a .