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Báo cáo khoa học: " Exceptionally high incidence of symptomatic grade 2–5 radiation pneumonitis after stereotactic radiation "

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Exceptionally high incidence of symptomatic grade 2–5 radiation pneumonitis after stereotactic radiation. | Radiation Oncology BioMed Central Research Exceptionally high incidence of symptomatic grade 2-5 radiation pneumonitis after stereotactic radiation therapy for lung tumors Hideomi Yamashita Keiichi Nakagawa Naoki Nakamura Hiroki Koyanagi Masao Tago Hiroshi Igaki Kenshiro Shiraishi Nakashi Sasano and Kuni Ohtomo Open Access Address Department of Radiology University of Tokyo Hospital Japan Email Hideomi Yamashita - yamachan07291973@yahoo.co.jp Keiichi Nakagawa - nakagawa-rad@umin.ac.jp Naoki Nakamura - nnakamur-tky@umin.ac.jp Hiroki Koyanagi - t34059@yahoo.co.jp Masao Tago - tago-rad@h.u-tokyo.ac.jp Hiroshi Igaki - igaki-tky@umin.ac.jp Kenshiro Shiraishi - kshiraishi-tky@umin.ac.jp Nakashi Sasano - sasanon-tky@umin.ac.jp Kuni Ohtomo - kotomo-tky@umin.ac.jp Corresponding author Published 7 June 2007 Received 17 April 2007 Radiation Oncology 2007 2 21 doi 10.1186 1748-717X-2-21 Accepted 7 June 2007 This article is available from http www.ro-journal.cOm content 2 1 21 2007 Yamashita et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background To determine the usefulness of dose volume histogram DVH factors for predicting the occurrence of radiation pneumonitis RP after application of stereotactic radiation therapy SRT for lung tumors DVH factors were measured before irradiation. Methods From May 2004 to April 2006 25 patients were treated with SRT at the University of Tokyo Hospital. Eighteen patients had primary lung cancer and seven had metastatic lung cancer. SRT was given in 6-7 fields with an isocenter dose of 48 Gy in four fractions over 5-8 days by linear accelerator. Results Seven of the 25 patients suffered from RP of symptomatic grade 2-5 according to the NCI-CTC version 3.0. The overall incidence rate of