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Báo cáo khoa học: "nalgesic Effect of Meloxicam in Canine Acute Dermatitis – a Pilot Study"

Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: Analgesic Effect of Meloxicam in Canine Acute Dermatitis – a Pilot Study. | Acta vet. scand. 2002 43 247-252. Analgesic Effect of Meloxicam in Canine Acute Dermatitis - a Pilot Study By O. Viking Hoglund and J. Frendin Arninge Djurklinik Tăby and Department of Large Animal Clinical Sciences Faculty of Veterinary Medicine Swedish University of Agricultural Sciences Uppsala Sweden. Viking Hoglund O. and Frendin J Analgesic effect of meloxicam in canine acute dermatitis - a pilot study. Acta vet. scand. 2002 43 247-252. - A double-blind trial was performed on 12 client-owned dogs suffering from acute and painful dermatitis. Clinically these cases represented pyotraumatic dermatitis and pyotraumatic folliculitis. Six dogs were injected with meloxicam and 6 were given placebo. Signs of pain were recorded on a visual analogue scale before administering the drug. This was repeated over the following 2-3 days. All dogs were treated with cephalexin orally. Six dogs given meloxicam and cephalexin showed an average decrease of pain on day 2 of 28.3 whereas the 6 dogs given placebo and cephalexin showed an average decrease of pain on day 2 of 8.3 . When compared in the Wilcoxon two-sample test using change in percent and absolute change the 2 groups yielded p 0.026 and p 0.064 respectively. These findings indicate that meloxicam has an analgesic effect on acute dermatitis in dogs. dermatitis meloxicam NSAID analgesic canine dogs pain. Introduction The effect of nonsteroidal anti-inflammatory drugs NSAID on dermatitis is well known from human trials and research using rats and mice Bayerl et al. 1998 Snyder 1975 Fleischer 1999 . To the best of our knowledge only one study has been published showing whether any of the modern NSAID impact the inflammatory process in acute dermatitis in the canine species Kimura Doi 1998 . According to data sheets for medicines indicated for usage in humans and animals meloxi-cam hinders the accumulation of leukocytes in inflamed skin and other tissues Medical Products Agency 2002 . In addition pruritus is a known side .