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Báo cáo khoa học: "PAC-Man: Game over for the pulmonary artery catheter"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: PAC-Man: Game over for the pulmonary artery catheter? | Available online at http ccforum content 10 1 303 University of Pittsburgh Department of Critical Care Medicine Evidence-Based Medicine Journal Club EBM Journal Club Section Editor Eric B. Milbrandt MD MPH Journal club critique PAC-Man Game over for the pulmonary artery catheter Michael C. Reade1 and Derek C. Angus2 1 Clinical Fellow Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA 2 Professor CRISMA Laboratory Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA Published online 6 January 2006 This article is online at http ccforum content 10 1 303 2006 BioMed Central Ltd Critical Care 2006 10 303 DOI 10.1186 cc3977 Expanded Abstract Citation Harvey S Harrison DA Singer M Ashcroft J Jones CM Elbourne D Brampton W Williams D Young D Rowan K Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care PAC-Man a randomized controlled trial. Lancet 2005 366 472477 1 . Background Over the past 30 years the pulmonary artery catheter PAC has become a widely used hemodynamic monitoring device in the management of the critically ill. However doubts have been raised regarding its benefits and safety. The aim of this study was therefore to ascertain whether hospital mortality is reduced in critically ill patients when they are managed with a PAC. Methods Design and setting Prospective randomized controlled trial of 1041 subjects enrolled in 65 British ICUs. Subjects and intervention Patients identified by the treating physician as someone who should be managed using invasive hemodynamic monitoring were randomized to management with n 519 or without n 522 a PAC. Subsequent clinical management was at the discretion of the treating clinician. Patients allocated to management with a PAC had the catheter placed as soon as possible after randomization. ICUs were stratified a priori depending on whether they wished