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Báo cáo khoa học: "N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock. | Available online http ccforum.eom content 11 2 R37 Research N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock Djamel Mokart1 Antoine Sannini1 Jean-Paul Brun1 Marion Faucher1 Didier Blaise2 Jean- Louis Blache1 and Catherine Faucher2 Department of Anesthesiology and Intensive Care Unit Paoli-Calmette Institute 232 bd Sainte Marguerite 13273 Marseille Cedex 9 France department of Hematology Paoli-Calmette Institute 232 bd Sainte Marguerite 13273 Marseille Cedex 9 France Corresponding author Djamel Mokart mokartd@marseille.fnclcc.fr Received 23 Oct 2006 Revisions requested 13 Dec 2006 Revisions received 22 Feb 2007 Accepted 14 Mar 2007 Published 14 Mar 2007 Critical Care 2007 11 R37 doi 10.1186 cc5721 This article is online at http ccforum.com content 11 2 R37 2007 Mokart et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The overall prognosis of critically ill patients with cancer has improved during the past decade. The aim of this study was to identify early prognostic factors of intensive care unit ICU mortality in patients with cancer. Methods We designed a prospective consecutive observational study over a one-year period. Fifty-one cancer patients with septic shock were enrolled. Results The ICU mortality rate was 51 26 deaths . Among the 45 patients who benefited from transthoracic echocardiography evaluation 17 showed right ventricular dysfunction 18 showed left ventricular diastolic dysfunction 18 showed left ventricular systolic dysfunction and 11 did not show any cardiac dysfunction. During the first three days of ICU course N-terminal pro-brain natriuretic peptide NT-proBNP levels were significantly higher in .