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Báo cáo y học: "Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: "Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease. | Retrovirology BioMed Central Research Open Access Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease Hong Zhang1 2 Federico Hoffmann2 Jun He1 2 Xiang He1 2 Chipepo Kankasa3 John T West1 2 Charles D Mitchell4 Ruth M Ruprecht5 6 Guillermo Orti2 and Charles Wood 1 2 Address 1Nebraska Center for Virology University of Nebraska Lincoln NE USA 2School of Biological Sciences University of Nebraska Lincoln NE USA 3Department of Pediatrics University Teaching Hospital Lusaka Zambia 4Department of Pediatrics University of Miami School of Medicine Miami FL USA 5Department of Cancer Immunology and AIDS Dana-Farber Cancer Institute Boston MA USA and 6Department of Medicine Harvard Medical School Boston MA USA Email Hong Zhang - hongz@unlserve.unl.edu Federico Hoffmann - federico@unlserve.unl.edu Jun He - jhe1@unl.edu Xiang He - xhe@unlserve.unl.edu Chipepo Kankasa - ckankasa@zamnet.zm John T West - john-west@ouhsc.edu Charles D Mitchell - cmitchel@med.miami.edu Ruth M Ruprecht - ruth_ruprecht@dfci.harvard.edu Guillermo Orti - gorti@unl.edu Charles Wood - cwood1@unl.edu Corresponding author Published 20 October 2006 Received 24 May 2006 Accepted 20 October 2006 Retrovirology 2006 3 73 doi l0.ll86 l 742-4690-3-73 This article is available from http www.retrovirology.cOm content 3 1 73 2006 Zhang et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The causal mechanisms of differential disease progression in HIV-1 infected children remain poorly defined and much of the accumulated knowledge comes from studies of subtype B infected individuals. The applicability of such findings to other subtypes such as subtype C remains to be substantiated. .