During the annual meeting of the Medical Society of Athens on November 15, 1930 Benediktos Adamantiades (1875-1962) (Fig. 1), Greek ophthalmologist from Prussa, Asia minor (nowadays Bursa, Turkey) 1-3 , presented in a lecture with the title ”A case of relapsing iritis with hypopyon ”, a 20-year-old male patient with the three cardinal signs of the disease. The disease had begun at the age of 18 with edema and ulcerations at the left leg diagnosed as thrombophlebitis. During the following 2 years (1928-1930) the patient was developing recurrent iritis with hypopyon in both eyes which led to.