One of the most popular organic pesticides, neem, is toxic to non-target species including crustaceans and tadpoles. Neem has been shown to cause the brain disease toxic encephalopathy in children. In mice, it causes chromosomal abnormalities in bone marrow cells and damages the DNA of sperm . Are there any other problems with organic pesticides? We really do not know simply because they are not regulated like the “synthetic” ones. Many organic products have never been tested for safety, but they are used under the guise that they are “natural” and are therefore not “chemicals”