Since its founding,ANAC has shown a singular commitment to improving the lives of those affected by HIV/AIDS. Nowhere is this commitment more fully articulated than in ANAC’s Core Curriculum for HIV/AIDS Nursing. Drawing from the expertise of frontline clinicians and scholars, the first two editions of the Core Curriculum provided nurses with the evidence-based knowledge to provide quality care to the diverse groups that comprise the HIV/AIDS population. In this third edition, we have endeavored to uphold the standard of excellence set by the editors of the first two editions. The clinical management of HIV/AIDS is constantly evolving, thus the third edition of the Core Curriculum has.