Purified manganese peroxidase (MnP) fromPhanerocha-ete chrysosporiumoxidizes nonphenolicb-1 diarylpropane lignin model compounds in the presence of Tween 80,and in three- to fourfold lower yield in its absence. In thepresence of Tween 80,1-(3¢,4¢-diethoxyphenyl)-1-hydroxy-2-(4¢-methoxyphenyl)propane (I) was oxidized to 3,4-diethoxy-benzaldehyde (II),4-methoxyacetophenone (III) and 1-(3¢,4¢-diethoxyphenyl)-1-oxo-2-(4¢-methoxyphenyl)pro-pane (IV),while only 3,4-diethoxybenzaldehyde (II) and 4-methoxyacetophenone (III) were detected when the reac-tion was conducted in the absence of Tween 80