Observation of Keratin pearl (KP) and individual cell keratin (ICK) is one of the criteria in grading oral squamous cell carcinoma (SCC). The aim of the study was to evaluate and compare the distinct staining and identification of KP and ICK by routine Hematoxylin and Eosin (H&E) stain Modified Mallory’s and Modified Papanicolaou Stain. A total number of 38 paraffin embedded tissues of known cases of well-differentiated and moderately-differentiated SCC were taken and 3 sections of 4-5 micron thickness from each block were cut and stained with H&E stain, Modified Mallory’s and modified Papanicolou stain. The KP and ICK were distinctly and clearly stained by modified Papanicolou, modified Mallory’s stain compared to H&E stain. | Comparison of staining of keratin pearl and individual cell keratin in oral squamous cell carcinoma by modified papanicolaou modified mallory s and hematoxylin and eosin stain
