Seven known compounds, including two neolignans, four lignans, and one flavane were isolated from the methanol extract of Pandanus tonkinenis fruits. Their structures were determined to be ficusal, vladinol F, medioresinol, syringaresinol, lariciresinol, secoisolariciresinol, and luteoliflavan by analysis of MS and NMR data as well as by comparison of their spectral data with those reported in the literature. | Cite this paper Vietnam J. Chem. 2023 61 S1 1-7 Research article DOI The chemical composition from the fruits of Pandanus tonkinensis their NO production inhibitory and lipid peroxidation inhibitory activities Dinh Thi Huyen Trang1 6 Pham Thu Trang2 Do Minh Phuong2 Duong Hong Anh2 3 Ngo Quoc Anh1 4 Phan Van Kiem1 5 and Pham Hung Viet2 1 Graduate University of Science and Technology VAST 18 Hoang Quoc Viet Cau Giay Hanoi 10000 Viet Nam 2 Key Laboratory of Analytical Technology for Environmental Quality amp Food Safety Control University of Science Vietnam National University Hanoi 334 Nguyen Trai Hanoi 10000 Viet Nam 3 Research Centre for Environmental Technology and Sustainable Development University of Science Vietnam National University Hanoi 334 Nguyen Trai Hanoi 10000 Viet Nam 4 Institute of Chemistry Vietnam Academy of Science and Technology 18 Hoang Quoc Viet Cau Giay Hanoi 10000 Viet Nam 5 Institute of Marine Biochemistry Vietnam Academy of Science and Technology 18 Hoang Quoc Viet Cau Giay Hanoi 10000 Viet Nam 6 College of Education Vinh University 182 Le Duan Truong Thi Vinh City Nghe An 43000 Viet Nam Submitted November 16 2022 Revised January 18 2023 Accepted February 7 2023 Abstract Seven known compounds including two neolignans four lignans and one flavane were isolated from the methanol extract of Pandanus tonkinenis fruits. Their structures were determined to be ficusal 1 vladinol F 2 medioresinol 3 syringaresinol 4 lariciresinol 5 secoisolariciresinol 6 and luteoliflavan 7 by analysis of MS and NMR data as well as by comparison of their spectral data with those reported in the literature. All compounds were evaluated for NO production inhibitory and lipid peroxidative inhibitory activities. Compounds 5 and 7 showed significant NO production inhibitory with IC50 values of and µM respectively. Compounds 6 and 7 showed significant lipid peroxidative inhibitory activity with IC50 values of and µM
